Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4717)
Related Products (4717)
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Gemcadiol
0 ImagesCat. No.: HY-121583CAS No.: 35449-36-6Gemcadiol is a potent antilipemic agent. Gemcadiol has the potential for the research of hyperlipoproteinemia.
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Bimatoprost methyl ester
0 ImagesCat. No.: HY-B0191BCAS No.: 38315-47-8
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N3-VC-PAB-PNP
0 ImagesCat. No.: HY-153486CAS No.: 2285374-43-6
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Secoisolariciresinol (Standard)
0 ImagesSynonyms: (-)-Secoisolariciresinol (Standard)Artemether (Standard) ((-)-Secoisolariciresinol (Standard)) is the analytical standard of Artemether (HY-N6071). This product is intended for research and analytical applications. Secoisolariciresinol ((-)-Secoisolariciresinol) is a plant lignan and a precursor of enterolignans. Secoisolariciresinol can be converted into enterodiol and enterolactone by intestinal microflora. Secoisolariciresinol may reduce the risk of cancer and cardiovascular diseases.
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JNJ-27548547
0 ImagesCat. No.: HY-185585CAS No.: 303983-00-8JNJ-27548547, Mitomycin C (HY-13316) prodrug, is a Mitomycin C and lipophilic group conjugate. JNJ-27548547 undergoes thiolytic cleavage of its dithiobenzyl linker in the presence of reducing agents to release active substance Mitomycin C. JNJ-27548547 is formulated into pegylated liposomes (PL-MLP) with high antitumor activity in mice models.
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Cassialoin
0 ImagesCat. No.: HY-N21609CAS No.: 60462-09-1Cassialoin is an orally active anthrone-C-glucoside natural product with antitumor activity, which is found in the heartwood of Cassia garrettiana. Cassialoin is metabolized to the active substance Chrysophanol‑9‑anthrone. Cassialoin does not directly inhibit the activities of VEGFR‑2 and MMP‑9 in vitro, nor does it directly inhibit vascular lumen formation and cell migration in vitro. Cassialoin increases the number of IFN-γ-positive CD8+ T cells and natural killer cells in the small intestine or spleen, and enhances IFN-γ production by splenocytes induced by Concanavalin A (HY-P2149). Cassialoin inhibits tumor growth and peritoneal invasion in colon cancer xenograft models. Cassialoin can be used for research on colon cancer.
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1-Methylpyrrolidine-d8
0 ImagesCat. No.: HY-128383SCAS No.: 131857-29-91-Methylpyrrolidine-d8 is the deuterium labeled 1-Methylpyrrolidine (HY-128383). 1-Methylpyrrolidine is a methylated pyrrolidine, and cation with thermal-origin negative nonlinear optical (self-defocusing) properties.
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2-(4-Bromophenoxy)ethanol
0 ImagesCat. No.: HY-44408CAS No.: 34743-88-92-(4-Bromophenoxy)ethanol is a Benzene compound and an intermediate.
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L-Ribose (Standard)
0 ImagesCat. No.: HY-W008351RCAS No.: 24259-59-4L-Ribose (Standard) is the analytical standard of L-Ribose (HY-W008351). This product is intended for research and analytical applications. L-Ribose is the enantiomer of D-ribose (HY-113375). L-Ribose replaces D-ribose to synthesize L-ribonucleic acid in cells, leading to erroneous gene transcription. L-Ribose serves as a starting material for L-nucleoside analogs, glycoconjugates and oligonucleotides. L-Ribose can be used in research related to hepatitis B virus infection, hepatitis C virus infection, hepatitis D virus infection, Epstein-Barr virus infection and cytomegalovirus infection.
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Antitumor agent-29
0 ImagesCat. No.: HY-139735CAS No.: 2847856-44-2Antitumor agent-29 is a novel hepatocyte-targeting antitumor proagent, which exhibits good antitumor activity and low toxic side effects.
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Quazolast
0 ImagesCat. No.: HY-106083CAS No.: 86048-40-0Synonyms: RHC 3988Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.
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BOC-L-Phenylalanine-13C
0 ImagesCat. No.: HY-79096SCAS No.: 84771-22-2BOC-L-Phenylalanine-13C is a 13C-labeled BOC-L-Phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent.
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(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (Standard)
0 ImagesCat. No.: HY-20302RCAS No.: 80875-98-5(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (Standard) is the analytical standard of (2S,3AS,7aS)-Octahydroindole-2-carboxylic acid (HY-20302). This product is intended for research and analytical applications. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid is a bicyclic hydrophobic proline analog that acts as a polyproline-II helix stabilizer. (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid serves as a structural component of Perindopril (HY-B0130). (2S,3aS,7aS)-Octahydroindole-2-carboxylic acid can be used in studies related to organic synthesis.
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Pyrrole-2-carboxylic acid (Standard)
0 ImagesCat. No.: HY-W001963RCAS No.: 634-97-9Pyrrole-2-carboxylic acid (Standard) is the analytical standard of Pyrrole-2-carboxylic acid (HY-W001963). This product is intended for research and analytical applications. sp. Nov. Pyrrole-2-carboxylic acid shows antibacterial activity and inhibits biofilm formation. Pyrrole-2-carboxylic acid serves as a precursor for various pyrrole derivatives like Clorobiocin (HY-123515), Coumermycin A1 (HY-N7452) in biosynthetic processes.
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Hemoregulatory peptide 5b
0 ImagesCat. No.: HY-P2158CAS No.: 84588-89-6Hemoregulatory peptide 5b is an acidic pentapeptide and also a selective inhibitor of myeloid hematopoiesis. Hemoregulatory peptide 5b inhibits myeloid hematopoietic colony formation, as well as the proliferation of committed myeloid hematopoietic stem cells and differentiating myeloid cells. Hemoregulatory peptide 5b exerts anticancer effects against mouse breast cancer and rat glioma. Hemoregulatory peptide 5b exhibits dose-dependent complex hematopoietic regulatory effects in vivo. Hemoregulatory peptide 5b can be used in research related to breast cancer, glioma, and lymphoma.
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Xanomeline-NH-Boc
0 ImagesCat. No.: HY-186320CAS No.: 1018846-42-8Xanomeline-NH-Boc is a derivative of Xanomeline (HY-105182), which serves as the orthosteric pharmacophore of M1/M4 muscarinic agonist 4 (HY-187957) for activating mAChR1/4.
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Fmoc-Aeg-OtBu
0 ImagesCat. No.: HY-P11692CAS No.: 169396-89-8Fmoc-Aeg-OtBu is an intermediate in solid-phase peptide synthesis, and serves as a building block for introducing pseudoproline motifs or backbone modifications.
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1-Hydroxy-3-oxodecane-1-sulfonate sodium
0 ImagesCat. No.: HY-186168CAS No.: 118019-64-01-Hydroxy-3-oxodecane-1-sulfonate sodium is a small-molecule acylacetaldehyde that can be used for the preparation of anti-inflammatory and bactericidal preparations.
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1-epi-Regadenoson ethyl ester
0 ImagesCat. No.: HY-Z9064CAS No.: 2015222-44-11-epi-Regadenoson ethyl ester is an intermediate in the synthesis of αisomer impurity of Regadenoson which is a highly selective adenosine A2A receptor agonist.
